Fig 7. Treatment of MDR A. baumannii human model using 100% efficient bacterial separation with antibiotic treatment.

Using this combination therapy, MDR A. baumannii clearance (≤ 1 CFU/mL) from the blood compartment of the human mathematical model occurred in 1 h. The time required for MDR A. baumannii to be cleared to a negligible concentration (≤1 CFU/mL) from the blood compartment with antibiotic administration alone was 29 h.