Skip to main content
. 2016 Sep 22;11(9):e0163533. doi: 10.1371/journal.pone.0163533

Table 1. Characteristics of case patients with acute coronary syndrome and control patients derived from a nationwide cohort with schizophrenia (N = 31,177).

Characteristic, n (%) Cases (n = 147) Controls (n = 2940) P-valuea
At first admission Mean (SD) Mean (SD)
 Age, years 45.7 (12.2) 45.6 (12.0) 0.131
n (%) n (%)
 Men 94 (64.0) 1880 (64.0)
 Charlson comorbidity index
  1 102 (69.4) 2457 (83.6) Reference
  2 35 (23.8) 400 (13.6) <0.001
  ≥3 10 (6.8) 83 (2.8) 0.002
Within 180 days before the index date
 Physical illnesses
  Diabetes mellitus 48 (32.7) 276 (9.4) <0.001
  Cerebrovascular disease 18 (12.2) 51 (1.7) <0.001
  Chronic hepatic disease 16 (10.9) 155 (5.3) 0.004
  Hypertension 57 (38.8) 354 (12.0) <0.001
  Asthma 10 (6.8) 48 (1.6) <0.001
 Concomitant drugs
  Drugs used in diabetes 48 (32.7) 249 (8.5) <0.001
  Antihypertensives 19 (12.9) 69 (2.4) <0.001
  Agents acting on the renin-angiotensin system 59 (40.1) 185 (6.3) <0.001
  Lipid modifying agents 36 (24.5) 125 (4.3) <0.001
  Corticosteroids for systemic use 39 (26.5) 260 (8.8) <0.001
  Nasal preparations 31 (21.1) 449 (15.3) 0.057
  Drugs for obstructive airway diseases 54 (36.7) 460 (15.7) <0.001
  Cough and cold preparations 83 (56.5) 1099 (37.4) <0.001
  Antihistamines for systemic use 71 (48.3) 972 (33.1) <0.001
  Mood stabilizer 26 (17.7) 467 (15.9) 0.560
  Antidepressant 37 (25.2) 571 (19.4) 0.088

aEstimated using univariate conditional logistic regression.