Fig 3. Contact zone size of cells after blocking CD11b or CD11c with antibodies.

Cells were divided into categories based on the size of their contact zones. MDMs (A) and MDDCs (B) were categorised into the following three groups: small ≤2000 pixel², medium 2000–400 pixel², large ≥4000 pixel². For monocytes (c) only 2 categories were established because of their smaller size (small ≤1000 pixel², large> 100 pixel²). 200 cells were counted for each cell type and each treatment, and the distribution between the different contact size categories was determined and is shown for MDDCs (D), MDMs (E) and monocytes (F). Results of one representative experiment of three independent ones is shown.