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. 2016 Sep 22;11(9):e0162955. doi: 10.1371/journal.pone.0162955

Fig 7. IGF-I treatment restores liver functionality and hepatocyte differentiation.

Fig 7

(a) Bilirubin and albumin were quantified in the serum of animals treated as described in Fig 1, 8 weeks after vector administration. (b) mRNA levels of the maturation factor HNF4α, the differentiation factor WT-1 and the proliferation factor PCNA were evaluated by qRT-PCR in liver extracts of animals described in Fig 1. Transcript levels shown are relative to GAPDH mRNA levels. Error bars denote standard deviations. Significant and non-significant (ns) differences are highlighted.