Table 2. SNPs associated with attention function outcomes at P<10−5 (ordered by significance).
| Attention outcome | SNP | CHR | position | Allelea | MAF | N | β | SE | P-value | Gene | Nearest gene |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Alerting | rs10015679 | 4 | 40644376 | T/C | 0.319 | 1491 | -13.80 | 3.00 | 4.10 x 10−6 | Intergenic | RBM47 |
| rs13048083 | 21 | 28286853 | T/C | 0.247 | 1491 | -14.48 | 3.23 | 7.33 x 10−6 | Intergenic | ADAMTS5 | |
| Orienting | rs10911457 | 1 | 183843104 | T/C | 0.461 | 1492 | 13.14 | 2.69 | 9.99 x 10−7 | RGL1 | - |
| rs12579294 | 12 | 3289945 | T/C | 0.222 | 1492 | -14.84 | 3.23 | 4.46 x 10−6 | TSPAN9 | - | |
| rs4629469 | 4 | 36419047 | G/A | 0.357 | 1490 | 12.76 | 2.82 | 5.95 x 10−6 | Intergenic | DTHD1 | |
| Executive Attention | rs2207190 | 1 | 171415856 | G/A | 0.405 | 1493 | -9.84 | 2.16 | 5.12 x 10−6 | Intergenic | PRRC2C |
| rs2320783 | 8 | 25009089 | G/A | 0.134 | 1493 | -14.27 | 3.17 | 6.82 x 10−6 | Intergenic | DOCK5 | |
| HRT | rs4775379 | 15 | 46682794 | T/C | 0.216 | 1484 | 35.87 | 7.23 | 6.98 x 10−7 | Intergenic | SQRDL |
| rs951738 | 13 | 45479633 | G/A | 0.234 | 1442 | 32.85 | 6.99 | 2.60 x 10−6 | Intergenic | NUFIP1 | |
| rs757594 | 17 | 12000632 | G/A | 0.233 | 1493 | 33.09 | 7.11 | 3.25 x 10−6 | MAP2K4 | - | |
| rs4321351 | 2 | 230129493 | G/A | 0.318 | 1493 | -28.99 | 6.24 | 3.35 x 10−6 | PID1 | - | |
| rs6593376 | 10 | 44469148 | T/C | 0.215 | 1493 | 32.31 | 7.08 | 5.02 x 10−6 | Intergenic | LINC00841 | |
| HRTSE | rs1560054 | 5 | 111519018 | T/C | 0.282 | 1493 | -16.95 | 3.59 | 2.29 x 10−6 | EPB41L4A | - |
SNP, single nucleotide polymorphism; CHR, chromosome; MAF, minor allele frequency; β, regression coefficient; SE, standard error.
a Effect allele/Other allele
RBM47, RNA binding motif protein 47; ADAMTS5, ADAM metallopeptidase with thrombospondin type 1 motif, 5; RGL1, Ral guanine nucleotide dissociation stimulator-like 1; TSPAN9, tetraspanin 9; DTHD1, death domain containing 1; PRRC2C, proline-rich coiled-coil 2C; DOCK5, dedicator of cytokinesis 5; SQRDL; sulfide quinone reductase-like; NUFIP1, nuclear fragile X mental retardation protein interacting protein 1; MAP2K4, dual specificity mitogen-activated protein kinase kinase 4; PID1, phosphotyrosine interaction domain containing 1; LINC00841, long intergenic non-protein coding RNA 841; EPB41L4A, erythrocyte membrane protein band 4.1 like 4.