Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Sep 16;9:5713–5720. doi: 10.2147/OTT.S110219

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2016 Zhai et al. This work is published and licensed by Dove Medical Press Limited

The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

PMC Copyright notice

The negative correlation between lncRNA HOTAIR and p53 expressions in NSCLC.

Notes: (A) Western blot assay showed the p53 protein level in 12 NSCLC patients’ samples, and β-actin was used as an endogenous control. The relative expressions of p53 in different samples were standardized to the No 1 by gray scale scanning, and the number below each band showed its relative p53 expression. (B) The relative expressions of lncRNA HOTAIR in the same patients’ samples with (A) detected by real-time PCR assay. (C) Real-time PCR assay showed the expression of the lncRNA HOTAIR in the cancer adjacent NT or CT in all 48 patients. (D) The correlation between the expressions of HOTAIR and p53 was analyzed with regression analysis. **P<0.01.

Abbreviations: CT, cancer tissues; HOTAIR, HOX antisense intergenic RNA; lncRNA, long noncoding RNA; NSCLC, non-small-cell lung cancer; NT, normal tissues; PCR, polymerase chain reaction.