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. 2016 Sep 16;9:5713–5720. doi: 10.2147/OTT.S110219

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© 2016 Zhai et al. This work is published and licensed by Dove Medical Press Limited

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lncRNA HOTAIR negatively correlates with p53 functionality.

Notes: (A) Western blot showed the p53 level in the A549 (p53 wild-type), NCI-H157 (p53 mutant), and H1299 (p53 deletion) cell lines, and the lncRNA HOTAIR level in these three cell lines were detected using real-time PCR (B). For all real-time PCR results, the formula 2^−ΔΔ^Ct was used, and data here were represented as mean ± SD of three independent experiments. **P<0.01.

Abbreviations: HOTAIR, HOX antisense intergenic RNA; lncRNA, long noncoding RNA; PCR, polymerase chain reaction; SD, standard deviation.