Fig 5. CD13 chemical inhibitors or antibodies significantly slow growth and migration of RA FLS in vitro.

FLS were seeded on 96-well plates overnight. An Essen Incucyte system was used for both growth (A) and migration (B) assays. Growth was calculated as the difference in percent confluence from time 0. Migration was measured in a scratch wound assay using relative wound density. All data is expressed as a ratio to untreated FLS of the same cell line. mean±SEM n≥4 (*p≤0.05)