Table 6B.
Multivariate Analysis of Prognostic Factors for Recurrence or Death for the Propensity Score Matched Patients (516; 172 in each group)
| Variable | Multivariate Analysis
|
||
|---|---|---|---|
| HR | 95% CI | P | |
| Age (continuous) | 1.03 | 1.01–1.04 | 0.002 |
| Sex | |||
| Female | Reference | — | — |
| Male | 0.83 | 0.59–1.16 | 0.27 |
| Smoking | |||
| Never | Reference | — | — |
| Former | 1.27 | 0.74–2.16 | 0.39 |
| Current | 1.99 | 1.07–3.71 | 0.031 |
| Clinical stage | |||
| IA | Reference | — | — |
| IB | 1.96 | 1.33–2.90 | < 0.001 |
| Pathologic type | |||
| Adenocarcinoma | Reference | — | — |
| Squamous cell carcinoma | 0.86 | 0.53–1.41 | 0.55 |
| Other | 0.80 | 0.43–1.49 | 0.48 |
| Cell differentiation | |||
| Well | Reference | — | — |
| Moderately | 1.60 | 1.02–2.50 | 0.042 |
| Poorly/undifferentiated | 2.61 | 1.55–4.40 | <0.001 |
| Unknown | 1.19 | 0.58–2.46 | 0.63 |
| FEV1 (continuous) | 1.00 | 0.99–1.01 | 0.88 |
| DLCO (continuous) | 0.985 | 0.975–0.995 | 0.002 |
| Approach | |||
| Robotic | Reference | — | — |
| Open | 1.12 | 0.73–1.74 | 0.60 |
| VATS | 1.44 | 0.92–2.26 | 0.11 |
CI, confidence interval; DFS, disease-free survival; DLCO, diffusing capacity of carbon monoxide; FEV1, forced expiratory volume in 1 second; HR, hazard ratio; VATS, video-assisted thoracic surgery.