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. Author manuscript; available in PMC: 2017 Oct 1.
Published in final edited form as: Hepatology. 2016 Jul 22;64(4):1057–1071. doi: 10.1002/hep.28680

Figure 6. Inhibition of SYK activation suppresses alcohol-induced liver steatosis.

Figure 6

C57BL/6 mice were fed a chronic alcohol or an isocaloric pair fed (PF) diet with SYK inhibitor (SYK Inh.) or vehicle treatment (+Veh.) as indicated. Liver steatosis was evaluated by Oil-RedO staining (A) and liver triglyceride assay (B). Liver RNA was analyzed for ADRP (C), PRDM16 (D) and UCP1 (E). A p-value <0.05 was considered statistically significant by ANOVA for 8–10 mice per experimental group (*, p<0.05 compared to baseline; #, p<0.05 compared to EtOH + vehicle group).