Figure 4. Developmental delays and histological abnormalities during the first wave of spermatogenesis in backcrossed Rhox13 KO mice.

There were no significant differences in the numbers of preleptotene spermatocytes at P8 (A–B) or leptotene (Lep) and zygotene (Zyg) spermatocytes at P12 (C–D). In contrast, P20 KO testes had significantly reduced numbers of round spermatids (RS) (E–F). Asterisk indicates significance at P=0.0002. Scale bar = 50 µm.