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. 2016 Sep 22;5(1):1644. doi: 10.1186/s40064-016-3326-7

Table 7.

Effect of latex and ethanolic leaf extract and abamectin on cardiac GSH content, LPO and GPx, GST and SOD activities in normal rats

Treatments Parameter
GSH (nmol/100 mg tissue) LPO (nmol/100 mg tissue) GPx (U/g tissue) GST (U/g tissue) SOD (U/g tissue)
4 weeks 8 weeks 4 weeks 8 weeks 4 weeks 8 weeks 4 weeks 8 weeks 4 week 8 weeks
Vehicle (CMC 1 %) control 163.34 ± 1.44a 143.42 ± 0.93b 46.31 ± 0.71f 47.85 ± 2.11f 84.85 ± 0.99a 85.50 ± 2.25a 489.93 ± 14.33ab 506.25 ± 3.74a 14.35 ± 0.18bc 15.31 ± 0.71ab
1/20 LD50 latex 109.87 ± 7.52cd 119.65 ± 8.74c 64.50 ± 3.68de 61.84 ± 1.13e 77.39 ± 2.04bc 69.00 ± 1.24defg 447.92 ± 2.69ef 481.80 ± 2.60bc 9.07 ± 0.23e 11.95 ± 0.29d
1/10 LD50 latex 69.69 ± 6.29e 97.71 ± 6.10d 72.82 ± 2.17cd 67.16 ± 2.65cde 69.93 ± 2.70defg 63.96 ± 0.43g 429.86 ± 12.39f 460.07 ± 6.63cde 1.93 ± 0.23h 4.62 ± 0.30g
1/20 LD50 ethanolic extract 68.39 ± 6.23e 108.40 ± 1.00cd 65.19 ± 3.75de 59.78 ± 4.33e 68.06 ± 1.69efg 79.63 ± 1.3ab 480.49 ± 13.70bc 454.51 ± 8.65de 15.71 ± 0.14a 6.84 ± 0.78f
1/10 LD50 ethanolic extract 45.35 ± 5.28f 102.50 ± 8.26cd 84.53 ± 4.66a 72.71 ± 2.56cd 63.96 ± 2.96g 77.11 ± 0.74bc 472.31 ± 5.63bcd 386.06 ± 8.17h 2.11 ± 0.25h 4.04 ± 0.06g
1/20 LD50 ABM 118.73 ± 11.35c 116.51 ± 4.20c 76.55 ± 6.46abc 72.56 ± 2.02cd 74.22 ± 2.59bcd 72.35 ± 3.33cdef 470.49 ± 3.39bcde 487.85 ± 0.77ab 13.39 ± 0.11c 7.12 ± 0.15f
1/10 LD50 ABM 77.61 ± 0.70e 77.43 ± 1.31e 84.30 ± 5.44ab 74.19 ± 3.12bcd 72.54 ± 2.35cde 84.85 ± 0.99a 447.92 ± 7.12ef 395.83 ± 3.36g 12.26 ± 0.22d 4.84 ± 0.38g
F-probability P < 0.001 P < 0.001 P < 0.001 P < 0.001 P < 0.001
LSD at 5 % level 17.2065 10.2926 6.0102 22.709 1.013
LSD at 1 % level 23.1723 13.8613 8.0941 30.5827 1.3642

Data are expressed as mean ± SE

Number of animals in each group is six

For each parameter, means, which do not share the same superscript symbol(s), are significantly different at P < 0.05