Table 7.
Treatments | Parameter | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
GSH (nmol/100 mg tissue) | LPO (nmol/100 mg tissue) | GPx (U/g tissue) | GST (U/g tissue) | SOD (U/g tissue) | ||||||
4 weeks | 8 weeks | 4 weeks | 8 weeks | 4 weeks | 8 weeks | 4 weeks | 8 weeks | 4 week | 8 weeks | |
Vehicle (CMC 1 %) control | 163.34 ± 1.44a | 143.42 ± 0.93b | 46.31 ± 0.71f | 47.85 ± 2.11f | 84.85 ± 0.99a | 85.50 ± 2.25a | 489.93 ± 14.33ab | 506.25 ± 3.74a | 14.35 ± 0.18bc | 15.31 ± 0.71ab |
1/20 LD50 latex | 109.87 ± 7.52cd | 119.65 ± 8.74c | 64.50 ± 3.68de | 61.84 ± 1.13e | 77.39 ± 2.04bc | 69.00 ± 1.24defg | 447.92 ± 2.69ef | 481.80 ± 2.60bc | 9.07 ± 0.23e | 11.95 ± 0.29d |
1/10 LD50 latex | 69.69 ± 6.29e | 97.71 ± 6.10d | 72.82 ± 2.17cd | 67.16 ± 2.65cde | 69.93 ± 2.70defg | 63.96 ± 0.43g | 429.86 ± 12.39f | 460.07 ± 6.63cde | 1.93 ± 0.23h | 4.62 ± 0.30g |
1/20 LD50 ethanolic extract | 68.39 ± 6.23e | 108.40 ± 1.00cd | 65.19 ± 3.75de | 59.78 ± 4.33e | 68.06 ± 1.69efg | 79.63 ± 1.3ab | 480.49 ± 13.70bc | 454.51 ± 8.65de | 15.71 ± 0.14a | 6.84 ± 0.78f |
1/10 LD50 ethanolic extract | 45.35 ± 5.28f | 102.50 ± 8.26cd | 84.53 ± 4.66a | 72.71 ± 2.56cd | 63.96 ± 2.96g | 77.11 ± 0.74bc | 472.31 ± 5.63bcd | 386.06 ± 8.17h | 2.11 ± 0.25h | 4.04 ± 0.06g |
1/20 LD50 ABM | 118.73 ± 11.35c | 116.51 ± 4.20c | 76.55 ± 6.46abc | 72.56 ± 2.02cd | 74.22 ± 2.59bcd | 72.35 ± 3.33cdef | 470.49 ± 3.39bcde | 487.85 ± 0.77ab | 13.39 ± 0.11c | 7.12 ± 0.15f |
1/10 LD50 ABM | 77.61 ± 0.70e | 77.43 ± 1.31e | 84.30 ± 5.44ab | 74.19 ± 3.12bcd | 72.54 ± 2.35cde | 84.85 ± 0.99a | 447.92 ± 7.12ef | 395.83 ± 3.36g | 12.26 ± 0.22d | 4.84 ± 0.38g |
F-probability | P < 0.001 | P < 0.001 | P < 0.001 | P < 0.001 | P < 0.001 | |||||
LSD at 5 % level | 17.2065 | 10.2926 | 6.0102 | 22.709 | 1.013 | |||||
LSD at 1 % level | 23.1723 | 13.8613 | 8.0941 | 30.5827 | 1.3642 |
Data are expressed as mean ± SE
Number of animals in each group is six
For each parameter, means, which do not share the same superscript symbol(s), are significantly different at P < 0.05