Table 8.
Treatments | Parameter | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
GSH (nmol/100 mg tissue) | LPO (nmol/100 mg tissue) | GPx (U/g tissue) | GST (U/g tissue) | SOD (U/g tissue) | ||||||
4 weeks | 8 weeks | 4 weeks | 8 weeks | 4 weeks | 8 weeks | 4 weeks | 8 weeks | 4 week | 8 weeks | |
Vehicle (CMC 1 %) control | 86.78 ± 9.11a | 69.60 ± 6.12b | 13.68 ± 1.72e | 14.46 ± 2.40e | 71.89 ± 3.25a | 73.20 ± 6.68a | 976.18 ± 23.75a | 1011.18 ± 27.05a | 10.24 ± 1.77a | 9.33 ± 0.97ab |
1/20 LD50 latex | 68.97 ± 3.94b | 33.41 ± 5.68e | 16.30 ± 0.56de | 23.33 ± 1.97bc | 50.85 ± 6.52cd | 44.53 ± 3.42cde | 683.16 ± 37.74bcd | 787.50 ± 52.34b | 6.45 ± 0.38cde | 5.12 ± 0.44defg |
1/10 LD50 latex | 54.24 ± 1.85cd | 28.32 ± 3.02ef | 29.76 ± 1.98a | 30.06 ± 3.02a | 48.50 ± 4.38cde | 46.99 ± 4.29cde | 637.50 ± 42.81cde | 769.38 ± 29.28b | 5.53 ± 0.54def | 4.40 ± 0.24efg |
1/20 LD50 ethanolic extract | 64.06 ± 2.18bc | 19.03 ± 0.55fg | 25.37 ± 2.67abc | 21.35 ± 1.73cd | 55.13 ± 3.69bc | 49.06 ± 1.37cd | 753.96 ± 33.91bc | 673.09 ± 76.22bcd | 7.93 ± 0.98bc | 6.36 ± 0.56cde |
1/10 LD50 ethanolic extract | 48.05 ± 1.77d | 14.87 ± 0.59g | 28.10 ± 2.42ab | 22.56 ± 1.65bc | 49.44 ± 2.15cd | 37.27 ± 3.28e | 489.58 ± 6.99f | 584.21 ± 47.88def | 7.13 ± 0.46cd | 3.07 ± 0.76g |
1/20 LD50 ABM | 53.45 ± 4.58cd | 31.06 ± 3.74e | 21.72 ± 1.61cd | 21.80 ± 1.50cd | 64.25 ± 3.05ab | 51.47 ± 2.67cd | 672.29 ± 21.79bcd | 596.88 ± 66.45def | 6.99 ± 0.80cd | 4.05 ± 0.37fg |
1/10 LD50 ABM | 48.87 ± 3.79d | 18.42 ± 0.96fg | 23.33 ± 0.87bc | 27.92 ± 1.99ab | 52.10 ± 3.18cd | 41.90 ± 3.22de | 569.17 ± 29.95def | 546.87 ± 51.57ef | 5.06 ± 0.48defg | 3.59 ± 0.40fg |
F-probability | P < 0.001 | P < 0.001 | P < 0.001 | P < 0.001 | P < 0.001 | |||||
LSD at 5 % level | 11.946 | 5.6821 | 11.3121 | 124.2059 | 2.1784 | |||||
LSD at 1 % level | 16.0879 | 7.6522 | 15.2342 | 167.2704 | 2.9337 |
Data are expressed as mean ± SE
Number of animals in each group is six
For each parameter, means, which do not share the same superscript symbol(s), are significantly different at P < 0.05