Figure 6. Correlation of DNA methylation with gene expression.
Matched methylation and gene expression data from The Cancer Genome Atlas were plotted to illustrate the correlation for selected cancer testis antigens (CTAs): (A) MAGEA1, (B) PAGE2, (C) CT83, and (D) SMC1B. The x axes give the β value of the region of the CTA 200 bp upstream of the transcription start site (TSS200) as a degree of methylation. The y axes give the gene expression as log2 transformed 1+ reads per kilobase of transcript per million mapped reads values of RNAseq.