Table 5.
Treatment | Target:Control Ratio | |||||
24 Hour | 48 Hour | |||||
MT1-MMP ± SEM | MMP-11 ± SEM | 18S rRNA ± SEM | MT1-MMP ± SEM | MMP-11 ± SEM | 18S rRNA ± SEM | |
Control | 1.00 ± 0.02 | 1.00 ± 0.02 | 1.00 ± 0.02 | 1.00 ± 0.08 | 1.00 ± 0.04 | 1.00 ± 0.05 |
Collagen I | 1.00 ± 0.08 | 1.35 ± 0.10 | 0.90 ± 0.08 | 0.59 ± 0.06 | 1.27 ± 0.08 | 0.96 ± 0.04 |
Collagen IV | 0.60 ± 0.06 | 0.68 ± 0.08 | 0.58 ± 0.06 | 0.35 ± 0.10 | 0.71 ± 0.10 | 0.60 ± 0.05 |
Collagen V | 1.10 ± 0.10 | 1.65 ± 0.08 | 0.60 ± 0.06 | 0.96 ± .004 | 1.91 ± 0.08 | 0.56 ± 0.08 |
Con-A | 1.00 ± 0.14 | 1.35 ± 0.12 | 0.78 ± 0.08 | 0.82 ± 0.10 | 1.41 ± 0.14 | 0.80 ± 0.02 |
TGF-β | 0.95 ± 0.06 | 0.56 ± 0.06 | 0.60 ± 0.02 | 0.70 ± 0.12 | 1.67 ± 0.14 | 0.56 ± 0.10 |
Fibronectin | 1.18 ± 0.12 | 0.72 ± 0.08 | 0.58 ± 0.02 | 0.95 ± 0.32 | 2.16 ± 0.24 | 0.52 ± 0.01 |
IL-1β | 1.14 ± 0.02 | 0.78 ± 0.04 | 0.55 ± 0.02 | 1.09 ± 0.18 | 2.20 ± 0.24 | 0.48 ± 0.02 |
IL-2 | 1.33 ± 0.20 | 0.70 ± 0.08 | 0.50 ± 0.02 | 1.01 ± 0.02 | 1.57 ± 0.16 | 0.48 ± 0.02 |
IL-6 | 0.80 ± 0.04 | 0.74 ± 0.04 | 0.65 ± 0.02 | 0.75 ± 0.06 | 1.27 ± 0.08 | 0.68 ± 0.04 |