Table 1.
Leukocyte and differential counts in WT and P/I null mice. Randomly selected normal mice not subjected to the sham or CLP treatment, were anesthetized and the peripheral blood and peritoneal lavage collected for leukocyte content and differential analysis. Data are expressed as mean ± SEM. Total leukocytes for peripheral blood represents the absolute number of cells X 106/ ml and for peritoneal lavage represent the absolute number of cells X 106/ lavage. The values in parenthesis denote absolute number of the cells X 106. * p ≤ 0.05 absolute number of cells of the wild-type compared to respective P/I null mice. n represents the number of mice per each group.
| Source | Total Leukocytes (× 106) | Differential (%) | ||
| % Neutrophils | % Lymphocytes | % Monocytes | ||
| Peripheral blood | ||||
| WT (n = 4) | 10.4 ± 1.5 | 26 ± 2 (2.9 ± 0.5) * | 72 ± 3 (7.2 ± 0.6) * | 2 ± 1 (0.3 ± 0.1) |
| P/I null (n = 5) | 10.3 ± 1.4 | 69 ± 7 (6.8 ± 0.9) | 32 ± 6 (3.4 ± 0.5) | 2 ± 1 (0.2 ± 0.1) |
| Peritoneal Lavage | ||||
| WT (n = 6) | 3.8 ± 0.9 | 16 ± 1 (0.6 ± 0.2) | 19 ± 3 (0.8 ± 0.3) | 65 ± 5 (2.4 ± 0.7) |
| P/I null (n = 6) | 3.6 ± 1.2 | 3 ± 1 (0.2 ± 0.1) | 54 ± 5 (1.9 ± 0.4) | 43 ± 6 (1.5 ± 0.7) |