FIGURE 7.

Predicted coiled-coil probability and temperature factors versus sequence for the class-specific kinesins. A, kinesin-1; B, KIF3A; C, Eg5; and D, CENP-E. The COILS-28 probabilities are shown as a solid line with MARCOIL probabilities shown with a dashed line. The start residue of the helix α7 coil as determined in the x-ray crystal structure is highlighted in gray. The predicted starting residues of the coiled-coil for KIF3A, Eg5, and CENP-E do not agree with the observed coiled-coil in the x-ray structures.