FIGURE 1.
Effects of PK on various currents of native channels in isolated neonatal rat cardiomyocytes. Families of Cs+-mediated IKr (IKr-Cs), Ito, IK1, Ba2+-mediated L-type Ca2+ channel current (ICa-Ba), and INa recorded in control (Ctrl) and PK (200 μg/ml, 20 min)-treated neonatal rat ventricular myocytes along with the voltage protocols are shown. Specific native ion channel currents recorded from each PK-treated cell are normalized to the mean value of the corresponding currents recorded from control cells and summarized in the bar graph below the representative currents. **, p < 0.01 versus Ctrl; n = 8–11 cells from three independent treatments for each channel. Error bars, S.E.