FIGURE 7.
Neither KCNE1 nor KCNE2 protects hERG channels against PK-mediated cleavage. A, Western blot demonstrating hERG expression in control (Ctrl) or PK-treated hERG-HEK cells without or with KCNE1 or KCNE2 expression (n = 3). B, IhERG recorded from control or PK-treated hERG-HEK cells without or with KCNE1 or KCNE2 expression. Summarized IhERG amplitude is shown below the current traces. The numbers above the bar graphs indicate the number of cells examined from two independent experiments. **, p < 0.01 versus control. Error bars, S.E.