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Proposed contributions of LCAT and ACAT1 to cholesterol esterification in the retina
+, minor contribution; +++, significant contribution.
| Cholesterol-esterifying enzyme | Hypocholesterolemic retina |
Normocholesterolemic retina |
Hypercholesterolemic retina |
||
|---|---|---|---|---|---|
| Mice | Mice | Humans | Mice | Humans | |
| LCAT | +++ | +++ | +++ | +++ | +++ |
| ACAT1 | + | + | + | +++ | + |
