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. 2016 Sep 8;3(2):e23. doi: 10.2196/humanfactors.6029

Table 1.

Information, Motivation, and Behavioral skills (IMB) barriers to medication adherence for patients with type 2 diabetes mellitus identified through a literature review.

Identified barriers to diabetes medication adherence Sample No. of text messages
addressing barrier
Information


Not understanding what medication is for AAa and NHWb [48] 20

Not understanding why medication regimens change NHW [49] 22

Not taking medication when feeling well AA [50,51] 16

Seeing no immediate benefit from taking medication Racially Diverse [52] 16

Believing generic medication is not as good as proprietary drugs AA and NHW [53] 16

Believing medication is not important AA [50] 14

Believing it is acceptable to skip doses or stop medication Racially Diverse [54] 16

Believing that regularly taking medication will not help control blood glucose levels or prevent complications Racially Diverse [52,55] 15
Personal motivation


Believing medication is harmful AA and NHW [53] 23

Taking medication is unpleasant AA and NHW [48] 17

Fear of side effects AA and NHW [48] 20

Worried about consequences of long-term use Racially Diverse [55] 19

Worried about medication causing weight gain Racially Diverse [56] 15

Believing that consequences of diabetes are predetermined and therefore inevitable Racially Diverse [57] 15

Burnout (ie, tired of taking medication) Racially Diverse [55,56] 15

Fear of side effects related to insulin injectionc Racially Diverse [58] 21
Social motivation


Not being supported by family or friends to take medications AA [59],
Racially Diverse [60,61]
16

Help with adherence from family or friends leads to conflict. Racially Diverse [60] 16

Family or friends give annoying reminders to take medication Racially Diverse [62] 17

Feeling judged by others because you take medication Racially Diverse [63,64] 16

Close others are disapproving of or do not value taking medications Racially Diverse [58] 14

Feeling embarrassed when taking medication Racially Diverse [58] 22

Family priorities make it difficult to take medication regularly AA [65],
Racially Diverse [32,55]
18

Family or friends give inaccurate information about medication AA [65],
Racially Diverse [62]
20

Feeling judged by others because you take insulinc Racially Diverse [63] 22

Embarrassed to take insulin in publicc Racially Diverse [58] 13
Behavioral skills


Regimen is too complex NHW [49], Racially Diverse [56], AA and NHW [48] 17

Taking medication disrupts routine/life Racially Diverse [55,57] 15

Hard to read medication labels Racially Diverse [31] 17

Difficulty asking provider about medication-related problems AA and NHW [48] 18

Forgetting to take doses AA [50,66], Racially Diverse [31,52,54,55,57], NHW [49], AA and NHW [48] 14

Cost of medication AA [50], NHW [49], Racially Diverse [31,52], AA and NHW [53] 16

Forgetting to get refills. AA [50] 14

Difficulty getting refills (eg, transportation, finding a pharmacy that carries prescription and/or offers affordable options) Racially Diverse [31,52] 19

Not taking insulin because it interferes with daily activitiesc Racially Diverse [58] 22

Not knowing how to manage pain when injecting insulinc Racially Diverse [58] 15

aAA: African American.

bNHW: non-Hispanic white.

cOnly assessed among participants who were prescribed insulin.