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. Author manuscript; available in PMC: 2017 Mar 1.

Published in final edited form as: Ann Intern Med. 2016 Feb 2;164(5):313–322. doi: 10.7326/M15-0880

A) RW020 ELISA Titers (RW020 Env is homologous to the Ad26 Env insert); B) UG37 ELISA Titers (UG37 Env is 81.2% homologous to the Ad35 Env insert). Second vaccinations were at month 6 in Groups A and B, and month 3 otherwise. Boxes represent the 1^st and 3^rd quartiles (IQR). Red lines indicate median titer. Whiskers extend to the 5^th and 95^th percentiles. White/orange boxes represent negative/positive baseline Ad26 NAb (A) and Ad35 NAb (B) values. On the X-axis, B, 1 & 2 represent baseline and 4 weeks post first and second vaccinations respectively.

A) RW020 ELISA Titers (RW020 Env is homologous to the Ad26 Env insert); B) UG37 ELISA Titers (UG37 Env is 81.2% homologous to the Ad35 Env insert). Second vaccinations were at month 6 in Groups A and B, and month 3 otherwise. Boxes represent the 1^st and 3^rd quartiles (IQR). Red lines indicate median titer. Whiskers extend to the 5^th and 95^th percentiles. White/orange boxes represent negative/positive baseline Ad26 NAb (A) and Ad35 NAb (B) values. On the X-axis, B, 1 & 2 represent baseline and 4 weeks post first and second vaccinations respectively.