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. 2016 Sep 23;6:31414. doi: 10.1038/srep31414

Figure 2. Adiponectin elevation inhibits AngII-induced AAA formation.

Figure 2

(a) Representative photographs showing macroscopic view of AAA induced by AngII infusion (red arrow). (b) Luminal diameter of abdominal aortas. Control n = 8, AdGFP n = 12, AdAPN n = 8, **p < 0.01 vs AdGFP and AdAPN, *p < 0.05 vs AdGFP, ANOVA (c) Outer aortic diameter of abdominal aortas. Control n = 8, AdGFP n = 12, AdAPN n = 8 **p < 0.01 vs AGFP and AdAPN, *p < 0.05 vs AdGFP, ANOVA. (d) Percent of AngII-infused LDLR−/− mice injected AdAPN or Ad-GFP that developed advanced AAA. *p < 0.05 vs AdGFP (e) Sudan IV-stained en face aortic preparations showing abdominal atherosclerotic lesions and aneurysm. (f) Representative cross-sections of abdominal aortas from AngIIAdGFP and AngIIAdAPN showing atherosclerosis (magnification 10X).