Skip to main content
. 2016 Sep 23;6:31414. doi: 10.1038/srep31414

Figure 4. Adiponectin regulates AngII-mediated inflammatory and extracellular matrix gene expression in the aneurysmal wall.

Figure 4

Gene expression analysis of angiotensin type 1a receptor (AT1aR), MMP9, mast cell chymase, mast cell tryptase, smooth muscle cell marker (SM22α), T-lymphocyte marker (CD3e), collagen, α-actin and lysyl oxidase (LOX) in abdominal aorta of control (PBS-infused) (n = 8) and AngII-infused AdGFP (n = 12) or AdAPN (n = 8)-injected mice after 8 weeks after AngII infusion. AT1aR analyzed with n = 5/group. RNA samples from abdominal aorta were analyzed by QRT-PCR and normalized to TBP. *p < 0.05 vs Control, **p < 0.01 vs AdGFP and Control, ANOVA.