Table 3. Univariable and Multivariable Analysis of Prognostic Factors.

	Univariable analysis					Multivariable analysis
	comparator	N	median survival (95% CI) in months	Log rank (X2)	p-value	HR	95% CI	p-value
Median age (years)	≥65.5 vs. <65.5	35/32	24.3 (17.4–31.2) vs. 20.2 (7.0–33.5)	0.392	0.531	1.758	0 0.908–3.402	0.094
Gender	M/F	42/25	21.5 (12.0–31.0)vs. 26.1 (18.1–34.1)	0.447	0.504	0.742	0.375–1.470	0.393
T-status	T3 vs. T1 & T2	3/64	18.1 (4.4–31.7) vs. 22.8 (16.3–29.3)	0.517	0.472	1.509	0.191–11.898	0.696
N-status	N1 vs. N0	9/58	7.4 (5.5–12.9)vs. 20.2 (11.0–29.4)	6.272	0.012	5.375	1.225–23.584	0.026
Grade	G1vs.G2 & G3	4/63	28.5 (24.5–32.5)vs.17.2 (12.7–21.7)	4.877	0.027	2203252	0.896–2.431	0.98
VDAC1 score	<4 vs. ≥4	38/29	27.0 (19.1–34.9) vs. 17.8 (8.5–27.1)	4.239	0.039	1.544	0.794–3.0	0.021