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. 2016 Sep 23;6:33990. doi: 10.1038/srep33990

Table 2. Cytotoxicity of zephycandidine A (1) (IC50 in μM) against five cancer cell lines and a non-cancerous human Beas-2B cell linea.

Compound HL-60 A549 MCF-7 SW480 SMMC-7721 BEAS-2B Highest index of selectivity
1 1.98 6.49 3.44 6.27 7.03 20.08 10
cis-platin 3.12 8.95 18.48 11.37 9.82 13.30 4.3

aThe “Highest index of selectivity” is the ratio of the IC50 value for the Beas-2B cell line over the lowest cancer cell IC50 value. cis-Platin was used as a positive control.