Figure 5.
(A) Resected liver as a percentage of body weight was not significant (p=0.3141). (B) Blood loss is not significant between groups, although it appears that hNP treatment trends towards a reduction in blood loss (p=0.7273). (C) Survival curve following liver trauma. (D)Survival of animals at one hour following liver trauma. The hemostatic nanoparticle (hNP) treatment (PLA-PEG-GRGDS nanoparticles) are significant compared with control nanoparticles (PLA-PEG-GRADSP) and saline (Kaplan Meier Estimate with 95% confidence bounds; Control vs. Saline, p= 0.0436; Control vs. hNP, p= 0.000271; hNPs vs. Saline, p= 0.0347)
