Figure 5. Example of simulated acoustic intensity profiles overlaid on the region of sonicated visual areas (from subject ‘h1’).

(a) The acoustic intensity profile (30 by 30 mm²) of the sonication focus overlaid on a 3D rendering of the volumetric head MRI data. The shape of the acoustic coupling hydrogel is visible (surrounded by white arrows) while the sonication focus was formed in the targeted visual area (inset, colored acoustic intensity map with maximum I_sppa value within the simulated region-of-interest; in W/cm²). See also Supplementary Fig. S1. (b) The acoustic intensity profile projected on 3D-rendered brain sections from the same individual (from left to right, coronal section, rotated to show the mid-sagittal region of the brain). The white dotted lines indicate the boundaries of the simulated ROIs.