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. 2016 Sep 20;7:12789. doi: 10.1038/ncomms12789

Figure 1. Architecture of MloK1.

Figure 1

(a) Topology of one subunit with six transmembrane segments (orange); the C-terminus contains the CNBD (yellow). The voltage sensor (S1–4) and the pore (S5–6) are in the transmembrane region. Atomic model based on the cryo-EM MloK1 structure (PDB 4CHV, ref. 15), in (b) side and (c) top views, respectively. The CNBDs arrange in a wind mill-like fashion (yellow outlines). (d) High-resolution HS-AFM topograph of MloK1 in 2D crystals in presence of 100 μM cAMP. Scale bar: 15 nm. Full colour scale: 2 nm.