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RORα deficient mice show an anti-inflammatory profile. (A) Weight and body composition of single housed 12 week-old males RORαWT (white bar, n = 6) or RORα Hypo (black bar, n = 6) littermate. (B) Blood cytokines profile form RORαWT (n = 6) or RORα Hypo (n = 6) male mice. (C) CD4 (upper) or CD8 (lower) expression in splenocytes freshly isolated from the spleen of 12 week-old male RORαWT (white, n = 5) or RORα Hypo (black, n = 5) mice. *p < 0.05, **p < 0.01.
