Figure 1.
Delayed obesity development in male pair-fed NEXLPL−/− mice (n = 4 for wt-ad, n = 4 for wt-pf, n = 4 for ko-pf). A. Weekly body weight of male ad-fed WT control mice and pair-fed (pf) WT and NEXLPL−/− mice. B. Body composition of 42 wk male ad-fed WT control mice and pair-fed WT and NEXLPL−/− mice. C. Weekly food intake (FI) normalized by body weight (BW) for male ad-fed WT control mice and pair-fed WT and NEXLPL−/− mice. D. Respiratory quotient (RQ) of 42 wk male ad-fed WT control mice and pair-fed WT and NEXLPL−/− mice. E. Metabolic rate (MR) of 42 wk male ad-fed WT control mice and pair-fed WT and NEXLPL−/− mice. F. Average daily physical activity of 42 wk male ad-fed WT control mice and pair-fed WT and NEXLPL−/− mice. G. Comparison of real time physical activity over the three day calorimetry period between 42 wk male ad-fed and pair-fed WT control mice. H. Comparison of real time physical activity over the three day calorimetry period between 42 wk male pair fed WT and NEXLPL−/− mice.