Figure 2.
Pair feeding prevents obesity development in female pair-fed NEXLPL−/− mice (n = 4 for wt-ad, n = 4 for wt-pf, n = 4 for ko-pf). A. Weekly body weight of female ad-fed WT control mice and pair-fed (pf) WT and NEXLPL−/− mice. B. Body composition of 38 wk female ad-fed WT control mice and pair-fed WT and NEXLPL−/− mice. C. Weekly food intake (FI) normalized by body weight (BW) for female ad-fed WT control mice and pair-fed WT and NEXLPL−/− mice. D. Respiratory quotient (RQ) of 38 wk female ad-fed WT control mice and pair-fed WT and NEXLPL−/− mice. E. Metabolic rate (MR) of 38 wk female ad-fed WT control mice and pair-fed WT and NEXLPL−/− mice. F. Average daily physical activity of 38 wk female ad-fed WT control mice and pair-fed WT and NEXLPL−/− mice. G. Comparison of real time physical activity over the three day calorimetry period between 38 wk female ad-fed and pair-fed WT control mice. H. Comparison of real time physical activity over the three day calorimetry period between 38 wk female pair fed WT and NEXLPL−/− mice.