Table 3.

Running time (seconds) for warm-start versus cold-started FVA in quad-precision using Quad MINOS (two LPs are run for each reaction)

Model	Reactions	Warm-start	Cold-start	Speed-up
E. coli ME (reduced)	16126	11.2 h	>670 h	60 ×
T. maritima ME [3]	17535	∼78 h	>1940 h	25×