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. 2016 Sep 22;9:93. doi: 10.1186/s13045-016-0327-5

Table 1.

Inhibitory effect of alantolactone on different leukemia cell lines

Cell lines IC50 (μM)a
Alantolactone ADR
K562 2.75 ± 0.64 0.15 ± 0.08
K562/A02 2.73 ± 0.83 8.94 ± 3.79
HL60 3.26 ± 0.88 0.027 ± 0.022
HL60/ADR 3.28 ± 0.80 5.54 ± 1.21
THP-1 2.17 ± 0.72 0.06 ± 0.038
KG1a 2.75 ± 0.65 0.62 ± 0.15
Normal cell 26.37 ± 4.04 N/A

ADR adriamycin, used as a positive control

aAll values are the mean of three independent experiments