Figure 2.
ON factor dependence from the relative tension on the thick filament. Experimental data (shown in the inset, adapted by permission from Macmillan Publishers Ltd: Nature Linari et al., 2015, copyright 2016) refers to SM6 signal and a direct comparison with the model prediction is not possible (see text). Therefore, ON factor has been defined to assure (i) about 5% of ON motors a low forces (less than 0.1 T0), and (ii) a saturating effect at forces higher than 0.5 T0, where almost all motors are in the ON state.