Extended Data Figure 3. HIV-specific T-cell responses.

Total breadth (open squares) and magnitude (bars) of T-cell responses against HIV-1 overlapping peptides (OLPs) at the designated time points following administration of 3BNC117 (yellow arrows indicate infusions of 3BNC117 at 30 mg kg⁻¹). For all study participants, antiretroviral therapy was discontinued on day 2 after the first 3BNC117 administration. Blue arrows indicate the time of viral rebound. For study participants 710, 712 and 715 rebound occurred at week 19, 16 and 11, respectively. Baseline samples for study participant 710 and week 12 samples for study participant 714 were not available for ELISpot analysis. Overall, breadth, magnitude and protein specificity were heterogeneous among the study participants.