Table 3.
Associations between bacterial vaginosis and adverse outcomes among full-term infants (37 weeks or greater gestation), Washington State, 2003-2013 (N = 11,354), adjusted for gestational age, maternal age, and maternal race, and additionally adjusted for the presence of chorioamnionitis or meconium
| BV exposed | BV unexposed | aRR | 95 % CI | |||
|---|---|---|---|---|---|---|
| N = 2198 | N = 9156 | |||||
| n | % | n | % | |||
| Assisted ventilation at birth | 98 | 4.5 | 328 | 3.6 | 1.28 | 1.02–1.61 |
| additionally adjusted for chorioamnionitis | 98 | 4.5 | 328 | 3.6 | 1.28 | 1.02–1.61 |
| additionally adjusted for meconium | 98 | 4.5 | 328 | 3.7 | 1.22 | 0.97–1.53 |
| Admission to NICU at birth | 88 | 4.1 | 269 | 3.0 | 1.42 | 1.11–1.82 |
| additionally adjusted for chorioamnionitis | 88 | 4.1 | 269 | 3.0 | 1.45 | 1.13–1.85 |
| additionally adjusted for meconium | 88 | 4.1 | 267 | 3.0 | 1.34 | 1.05–1.72 |
| Neonatal sepsis | 48 | 2.2 | 125 | 1.4 | 1.60 | 1.13–2.27 |
| additionally adjusted for chorioamnionitis | 48 | 2.2 | 125 | 1.4 | 1.67 | 1.19–2.35 |
| additionally adjusted for meconium | 48 | 2.2 | 125 | 1.4 | 1.51 | 1.06–2.14 |
| Fetal Mortality | 3 | 0.1 | 12 | 0.1 | 1.15* | 0.27–4.96 |
| additionally adjusted for chorioamnionitis | 3 | 0.1 | 12 | 0.1 | 1.14* | 0.27–4.88 |
| additionally adjusted for meconium | 0 | 0.0 | 3 | 0.0 | - | - |
| Infant mortality | 3 | 0.1 | 24 | 0.3 | 0.39 | 0.12–1.28 |
| additionally adjusted for chorioamnionitis | 3 | 0.1 | 24 | 0.3 | 0.39 | 0.12–1.27 |
| additionally adjusted for meconium | 3 | 0.1 | 23 | 0.3 | 0.40 | 0.12–1.34 |
BV bacterial vaginosis, aRR adjusted risk ratio, CI confidence interval, NICU neonatal intensive care unit
*further adjusted for presence of sexually transmitted infections (syphilis, gonorrhea, chlamydia, and/or genital herpes)