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. 2016 Oct;44(10):1550–1561. doi: 10.1124/dmd.116.071183

TABLE 1.

Phenotype data for OATP1B1 (SLCO1B1)

Phenotype Diplotype Relative Abundance CV
%
ET *1a/*1a 1 74
*1a/*1b
*1a/*14
*1a/*35
IT *1a/*5 0.68 54
*1a/*15
*1b/*15
*5/*14
*14/*15
PT *5/*5 0.37 35
*15*15
*5/*15
UT *1b/*35 1.47 46
*1b/*14
*14/*35

Relative abundance and the related population variability of each phenotype was obtained from in-house meta-analysis of published studies (Tirona et al., 2001; Iwai et al., 2004; Kameyama et al., 2005; Nozawa et al., 2005; Ho et al., 2006, 2007; Couvert et al., 2008; Deng et al., 2008; Choi et al., 2011; de Graan et al., 2012; Lancaster et al., 2012; Nies et al., 2013). Diplotypes associated with each phenotype definition are also summarized. All combinations of a given diplotype have been included in the model (e.g., *1a/*1b and *1b/*1a) but for simplicity are not included in this table.