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. 2016 Oct;359(1):159–170. doi: 10.1124/jpet.116.235838

Fig. 3.

Fig. 3.

Effects of ketamine on parameters of dopamine release. (A) Percentage changes in the [DA]max of stimulation-evoked DA release at each stimulation after the drug treatment (predrug baseline = 100). (B) Percentage changes in rise time (the amount of time it takes to reach peak DA concentrations) at each stimulation during the release of DA (predrug baseline = 100). (C) Percentage changes in decay constant (tau) values at each stimulation during the falling phase of evoked DA (predrug baseline = 100). Two-way repeated-measures ANOVA; *p < 0.05, **p < 0.01 compared with the saline group, Holm-Šídák post-hoc test. Data are the mean ± S.E.M. (saline: n = 8; KET 2 mg/kg : n = 4; KET 10 mg/kg: n = 6; KET 50 mg/kg: n = 6; QNP: n = 5). KET, ketamine; QNP, quinpirole.