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Determination of the TTO in C57BL/6 mice after laser-induced arterial injury. C57BL/6 mice (n = 6–8) were administered either vehicle (control) or various doses of ClopNPT via the tail vein 30 minutes before laser-induced injuries. Blood vessel flow was monitored until occlusive thrombosis occurred as described in the Materials and Methods. PBS, phosphate-buffered saline.
