. Author manuscript; available in PMC: 2016 Sep 23.

Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2010 Jan 19;19(2):588–599. doi: 10.1158/1055-9965.EPI-09-0864

Table 6.

Association of common haplotypes with prostate cancer risk in Caucasian and African American men

SNP combination	Freq	No. of haplotypes		OR^* (95% CI)	P
Caucasians^†		Cases	Controls
*MSR1*: rs918-rs1904577-rs2127565-rs12718376-rs3747531-rs351572
G-A-C-G-C-G	39%	259	392	1.58 (1.23–2.04)	4.02 × 10⁻⁴
G-A-C-G-C-A	31%	208	346	1.10 (0.86–1.40)	0.443
G-A-C-A-C-A	8%	44	118	0.63 (0.44–0.90)	0.010
African Americans^‡
*ELAC2*: rs2072262-rs2523-rs11545302-rs8077923-rs7218504
C-A-A-A-C	30%	35	58	0.76 (0.48–1.20)	0.235
C-G-A-A-G	24%	29	51	0.64 (0.38–1.07)	0.090
C-A-A-A-G	17%	28	30	1.23 (0.73–2.08)	0.435
C-G-G-C-G	6%	15	6	3.65 (1.38–9.68)	0.009
G-G-A-A-G	5%	6	13	0.59 (0.21–1.65)	0.314

NOTE: Significant results after Bonferroni correction are in bold (P < 0.017 and P < 0.01 in Caucasians and African Americans, respectively).

Only common haplotypes (>5%) are shown.

OR is age adjusted.

^†

Dominant model.

^‡

Additive model.