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. 2016 Aug 28;2016(8):CD008815. doi: 10.1002/14651858.CD008815.pub4

Moore 1995.

Methods Design: retrospective chart review
Location: rural obstetrics and gynecology clinic in Arizona (USA)
Time frame: no information
Sample size estimation and outcome of focus: none; selected 50 women in each group who met inclusion criteria
Participants 150 women, 15 to 30 years old
Inclusion criteria: users of OCs, Norplant, or DMPA
Exclusion criteria: prior hormonal contraceptive therapy; height < 62 inches (152.4 cm) or > 70 inches (177.8 cm); weight < 100 lb (45.5 kg) or > 180 lb (81.8 kg); presence of diabetes; history of thyroid disease; < 12 months postpartum
Interventions 1) Norplant (N = 50)
 2) DMPA 150 mg (N = 50)
Third group of OC users excluded from this review; type of OC not specified and may have included progestin‐only OCs and combination OCs
Outcomes Weight gain (kg)
Timeframe: 1 year
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) High risk Women presumably chose contraceptive method; charts reviewed until 50 met eligibility criteria for each group
NOS selection (NRS) Low risk Exposed: rural clinic population
Non‐exposed: same population as exposed but used different contraceptive
Exposure: clinic records
NOS comparability (NRS) Low risk Analysis: model adjusted for age, height, weight, and parity at beginning of study period
Blinding of participants and personnel (performance bias) 
 All outcomes Unclear risk Not feasible because women presumably chose contraceptive method
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk No information; objective outcome measure
Incomplete outcome data (attrition bias) 
 All outcomes High risk Loss to follow‐up: retrospective review of charts with relevant data; does not account for discontinuation and loss