Moore 1995.
Methods | Design: retrospective chart review Location: rural obstetrics and gynecology clinic in Arizona (USA) Time frame: no information Sample size estimation and outcome of focus: none; selected 50 women in each group who met inclusion criteria |
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Participants | 150 women, 15 to 30 years old Inclusion criteria: users of OCs, Norplant, or DMPA Exclusion criteria: prior hormonal contraceptive therapy; height < 62 inches (152.4 cm) or > 70 inches (177.8 cm); weight < 100 lb (45.5 kg) or > 180 lb (81.8 kg); presence of diabetes; history of thyroid disease; < 12 months postpartum |
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Interventions | 1) Norplant (N = 50)
2) DMPA 150 mg (N = 50) Third group of OC users excluded from this review; type of OC not specified and may have included progestin‐only OCs and combination OCs |
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Outcomes | Weight gain (kg) Timeframe: 1 year |
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Notes | ||
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | High risk | Women presumably chose contraceptive method; charts reviewed until 50 met eligibility criteria for each group |
NOS selection (NRS) | Low risk | Exposed: rural clinic population Non‐exposed: same population as exposed but used different contraceptive Exposure: clinic records |
NOS comparability (NRS) | Low risk | Analysis: model adjusted for age, height, weight, and parity at beginning of study period |
Blinding of participants and personnel (performance bias) All outcomes | Unclear risk | Not feasible because women presumably chose contraceptive method |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | No information; objective outcome measure |
Incomplete outcome data (attrition bias) All outcomes | High risk | Loss to follow‐up: retrospective review of charts with relevant data; does not account for discontinuation and loss |