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. Author manuscript; available in PMC: 2016 Sep 23.
Published in final edited form as: Adv Exp Med Biol. 2010;693:37–53. doi: 10.1007/978-1-4419-7005-3_3

Table 1. Nucleotide sequence specificity of STAR domain proteins.

RNA recognition by STAR domain proteins. The STAR protein identity is listed in the first column. The second column contains the RNA-binding consensus sequence. Degenerate nucleotides are contained within parentheses. The third column annotates the experimental method used to measure the specificity.

Protein Specificity Method
GLD-1 5'-UACU(C/A)A-3' (conservative) 5'(U>C>G/A)A(C>A)U(C/A)A-3' (relaxed) Gel Shift / Mutagenesis36
QKIa 5'-A(C/A)UAA-3' FP / Mutagenesis44
QKIb 5'-ACUAA-3' (core) 5'-(U/C)AA(U/C)-3' (half-site) SELEX38
HOW 5'-A(C>A)UAA-3' Pull Down37
Sam68 5-UAAA-3' SELEX27
a

Binding specificity determined by Ryder and Williamson43

b

Binding specificity determined by Galarneau et al.37