Table 3.
Results of comparison of seizure features pre- and post-phenobarbital.
| Features | Summary measure | Pre-Pb seizures. [Median (IQR)] | Post-Pb seizures. [Median (IQR)] | p value⁎ |
|---|---|---|---|---|
| Peak amplitude (μV) | Median | 123 (62.5–225) | 53.5 (46.13–89.25) | 0.001 |
| Seizure duration (s) | Median | 103 (69.13–185.25) | 135 (62.63–235) | 0.420 |
| Number of EEG channels involved in seizure onset (n) | Median | 4 (2.38–4.25) | 3 (1–4) | 0.068 |
| Number of EEG channels involved at peak of seizure (n) | Median | 4 (3–8) | 3 (1.38–4) | 0.018 |
| Frequency variability (over whole seizure) Hz | Median | 0.25 (0.07–1.64) | 0.24 (0.06–1.85) | 0.868 |
| Rhythmicity score (1–3) | Maximum | 3 (2–3) | 3 (2–3) | 0.317 |
| Background EEG (1–4) | Maximum | 1.5 (1–4) | 1.5 (1–3.25) | 0.317 |
| Seizure detection rate | Proportion | 0.77 (0.23–0.93) | 0.73 (0.33–0.89) | 0.730 |
| Changed morphology | Proportion | 0.45 (0.11–0.88) | 31 (0.0–0.67) | 0.310 |
⁎
From Wilcoxon Signed Rank test. N.B. Comparisons of discharge morphology (RDD, RDT, RDA, SP/SH, SP + W/SH + W) at start and peak of seizure are omitted, p > 0.05 for all comparison.