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. 2016 Aug 4;214(8):1159–1163. doi: 10.1093/infdis/jiw346

Figure 1.

Figure 1.

Influenza A(H1N1)pdm09 virus seroconversion does not correlate with increased anti–influenza virus antibody-dependent cellular cytotoxicity (ADCC) responses in the community. A, Representative fluorescence-activated cell-sorting plots show the amount of ADCC (in bold) as the summed total of CD107a+ and/or interferon γ (IFN-γ)+ natural killer (NK) cells (CD14−CD3−CD56+). B and C, A(H1N1)pdm09 microneutralization (MN) assay positive (n = 17; black symbols), MN assay negative (n = 15; white symbols), and pooled serum (pooled from 4 Red Cross blood donors after the pandemic; gray symbols) were assessed for ADCC-activating antibody responses toward the H1 hemagglutinin (HA), H7 HA, and conserved nucleoprotein (NP). The amount of ADCC is the summed total of CD107a+ and/or IFN-γ+ (B) or IFN-γ+ (C) NK cells.