Fig 1. Genetic variants, identified in patients with RCM.

(a) Overall yield of genotype-positive (pathogenic and likely pathogenic) variants and variants of unknown significance according to ACMG classification. (b) Genes where pathogenic, likely pathogenic variants and variants of unknown significance were detected. Blue corresponds to the genes encoding for sarcomeric proteins, red—to the genes encoding for cytoskeletal proteins, green—to ion channels and purple to the other genes. (c) Combination of pathogenic variants, likely pathogenic variants and variants of unknown significance in patients with RCMP.