Table 4. Prognostic factors related to overall survival of patients.

	Univariate		Multivariate
Variable	HR	P	HR	p	95% CI
Gender	1.401	.118
Age ≥ 65 y	1.030	.179
KPS ≥ 70	0.218	.013	0.957	.011	0.055–0.501
Control of primary disease	0.344	.001	0.166	.001	0.043–0.326
Extracranial metastases	1.305	.294
Multiple metastases	1.154	.732
Tumor volume > 14cm3	0.996	.984

HR = hazard ratio; CI = confidence interval; KPS = Karnofsky performance status.