Figure 1. Spectra acquired from the phantom containing naturally abundant ¹³C Intralipid.

(A and B) The result from the conventional quantum coherence sequences. In both cases, the ¹³C chemical shift evolution during the t₁ period resulted in phase distortions in the spectrum. Addition of the ¹³C inversion pulse led to nonphase distorted lipid spectra, in which both CH₂ and CH₃ signals were observable. (C and D) Both relative and absolute signals were higher in the 1D ge-HSQC (heteronuclear single quantum coherence) as compared with the 1D ge-HMQC (heteronuclear multiple quantum coherence).