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. Author manuscript; available in PMC: 2017 Nov 1.
Published in final edited form as: Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2016 Mar 23;8(6):872–890. doi: 10.1002/wnan.1402

Figure 7.

Figure 7

Tumor therapy using GA-198AuNPs. (A) Therapeutic efficacy of GA-198AuNPs in prostate tumor–bearing SCID mice. Subcutaneous tumors were generated in SCID mice by PC-3 engraftment. Mice bearing palpable tumors were randomized for treatment (n = 7) and control (n = 7) groups followed by intratumoral (IT) injections of GA-198AuNPs (408 μCi per animal) or DPBS, respectively. Graph represents mean tumor volume following 30 days of treatment. (B) TEM image showing uptake of GA- AuNPs in PC-3 prostate cancer cells. Reprinted with permission from Shukla, R. et al. Laminin receptor specific therapeutic gold nanoparticles (198AuNP-EGCg) show efficacy in treating prostate cancer. Proc. Natl. Acad. Sci. 109, 12426–12431 (2012).