Table 5.

Univariate^* Analysis by Age Subgroup of Acute Grade ≥ 2 Toxicity by Trial

	RTOG 94-08 (n=104)	RTOG 96-01 (n=371)	p-value*
Age < 66	(n=20)	(n=201)
Acute Grade ≥ 2 urinary
Toxicity
Yes	9 (45.0%)	33 (16.4%)	0.0047†
No	11 (55.0%)	168 (83.6%)
Age ≥ 66	(n=84)	(n=170)
Acute Grade ≥ 2 urinary
Toxicity
Yes	23 (27.4%)	19 (11.2%)	0.0020†
No	61 (72.6%)	151 (88.8%)

^*Based on Fisher’s exact test

^†Statistical Significance